Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGRXD4)

Drug Name

Orthovanadate Drug Info

Synonyms

Vanadic acid; Vanadiumsaeure; trihydroxy(oxo)vanadium; H3VO4; CHEMBL50626; CHEBI:27273; [VO(OH)3]; trihydroxidooxidovanadium; S6508_SIGMA; trihydrogen(tetraoxidovanadate); AC1L9D41; WQEVDHBJGNOKKO-UHFFFAOYSA-K; BDBM50284960

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 417214
ChEBI ID: CHEBI:27273
TTD Drug ID: DMGRXD4

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein-tyrosine phosphatase sigma (R-PTP-sigma)	TTCWXFA	PTPRS_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Protein-tyrosine phosphatase sigma (R-PTP-sigma)	DTT	PTPRS	4.65	4.278	2.406	4.453

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Protein-tyrosine phosphatase sigma (R-PTP-sigma)	DTT	PTPRS	1.17E-01	0.21	0.65

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Human protein tyrosine phosphatase-sigma: alternative splicing and inhibition by bisphosphonates. J Bone Miner Res. 1996 Apr;11(4):535-43.