Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMH4AKG)

Drug Name
PG-1014491 Drug Info
Synonyms PG-1014493; Farnesyl pyrophosphate synthase (FPS) bisphosphonate inhibitors (bone disorders), Procter & Gamble
Indication
Disease Entry ICD 11 Status REF
Bone disease FC0Z Investigative [1]
Cross-matching ID
TTD Drug ID
DMH4AKG

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Geranyltranstransferase (FDPS) TTIKWV4 FPPS_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Bone disease
ICD Disease Classification FC0Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Geranyltranstransferase (FDPS) DTT FDPS 7.06E-03 -0.73 -2.57
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 643).