Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMH4CFE)

Drug Name

Antithymocyte globulin Drug Info

Synonyms

Atgam (TN); Thymoglobulin (TN)

Indication

Disease Entry	ICD 11	Status	REF
Aplastic anemia	3A70	Approved	[1]

Therapeutic Class

Immunomodulatory Agents

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
T-cell surface glycoprotein CD1a (CD1A)	TTBGTFN	CD1A_HUMAN	Binder	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
T-cell surface glycoprotein CD1a (CD1A)	DTT	CD1A	6.528	6.589	6.534	6.615

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Aplastic anemia

ICD Disease Classification

3A70

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
T-cell surface glycoprotein CD1a (CD1A)	DTT	CD1A	6.30E-02	0.67	1.48

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Approval information for Divalproex Sodium (approved in 1996). 1996.
2	Acute sensory neuropathy associated with rabbit antithymocyte globulin. Am J Transplant. 2007 Feb;7(2):484-6.