Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHNSXP)

• Drug Name: 4-chloro-1H-indazole Drug Info
• Synonyms: 4-Chloro-1H-indazole; 13096-96-3; 4-CHLOROINDAZOLE; 1H-Indazole, 4-chloro-; 4-Chloro-2H-indazole; NSC694315; 4-CHLORO(1H)INDAZOLE; CHEMBL246533; MFCD00211065; 4-Chloro-1H-indazole, AldrichCPR; 4-chloro-indazole; zlchem 748; NSC 694315; PubChem21945; AC1Q3RSH; ACMC-1BUW0; AC1L95AW; SCHEMBL476854; 4-Chloro-1H-indazole, 97%; 4-CHLORO (1H)INDAZOLE; CTK0H7106; DTXSID40156818; ZLD0205; CQTGQYVQJOJQCM-UHFFFAOYSA-N; MolPort-001-767-756; 4-CHLORO-3-(1H)INDAZOLE; ACT06078; BCP27008; ZINC5543816; KS-00000O0T; CS-M0440; STL556259; SBB054691; QC-206

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 393037
  CAS Number: CAS 13096-96-3
  TTD Drug ID: DMHNSXP

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nitric-oxide synthase brain (NOS1)	TTZUFI5	NOS1_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	6.085	5.844	5.849	5.806

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	5.20E-01	0.02	0.07

References

• [1] 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80.