Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMHP8FI)

Drug Name
Methscopolamine Bromide Drug Info
Synonyms Pamine Forte
Indication
Disease Entry ICD 11 Status REF
Nausea and vomiting MD90 Approved [1]
Cross-matching ID
PubChem CID
5459110
ChEBI ID
CHEBI:61276
CAS Number
CAS 155-41-9
TTD Drug ID
DMHP8FI
ACDINA Drug ID
D00414

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Muscarinic acetylcholine receptor M3 (CHRM3) TTQ13Z5 ACM3_HUMAN Modulator [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Nausea and vomiting
ICD Disease Classification MD90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Muscarinic acetylcholine receptor M3 (CHRM3) DTT CHRM3 4.61E-07 -0.59 -0.73
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Agonist-regulated alteration of the affinity of pancreatic muscarinic cholinergic receptors. J Biol Chem. 1993 Oct 25;268(30):22436-43.