Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMI94L1)

Drug Name
REV-5901 Drug Info
Synonyms
Rev 5901; REV-5901; 101910-24-1; RG 5901; PF 5901; alpha-Pentyl-3-(2-quinolinylmethoxy)benzenemethanol; 1-[3-(quinolin-2-ylmethoxy)phenyl]hexan-1-ol; CHEMBL8747; MLS000069771; REV-901; PF-5901; SMR000058509; alpha-Pentyl-3-[2-quinolinylmethoxy]benzyl alcohol; Benzenemethanol, alpha-pentyl-3-(2-quinolinylmethoxy)-; 1-(3-(quinolin-2-ylmethoxy)phenyl)hexan-1-ol; SR-01000076105; ACMC-20d0wb; Opera_ID_512; WNW5RYD8MG; UNII-WNW5RYD8MG; AC1L1JIU; Lopac0_001042; CBiol_001910; KBioGR_000242; BSPBio_001522; KBioSS_000242; MLS001076522
Cross-matching ID
PubChem CID
5059
ChEBI ID
CHEBI:91821
CAS Number
CAS 101910-24-1
TTD Drug ID
DMI94L1

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Arachidonate 5-lipoxygenase (5-LOX) TT2J34L LOX5_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Arachidonate 5-lipoxygenase (5-LOX) DTT ALOX5 4.966 5.133 5.358 6.128
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Arachidonate 5-lipoxygenase (5-LOX) DTT ALOX5 7.42E-01 -0.18 -0.25
Arachidonate 5-lipoxygenase (5-LOX) DTT ALOX5 1.25E-03 0.43 0.63
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity. J Med Chem. 1991 Mar;34(3):1028-36.