Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMI9FXE)

Drug Name
KBP-5074 Drug Info
Indication
Disease Entry ICD 11 Status REF
Hypertension BA00-BA04 Phase 1/2 [1]
Cross-matching ID
PubChem CID
137796979
TTD Drug ID
DMI9FXE

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mineralocorticoid receptor (MR) TT26PHO MCR_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Mineralocorticoid receptor (MR) DTT NR3C2 5.85 7.414 6.42 7.379
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Hypertension
ICD Disease Classification BA00-BA04
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Mineralocorticoid receptor (MR) DTT NR3C2 7.31E-01 -5.31E-04 -1.53E-03
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)