Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMIVO8P)

Drug Name

N-Isopropyl-N'-Hydroxyguanidine Drug Info

Synonyms

N-ISOPROPYL-N'-HYDROXYGUANIDINE; N-HYDROXY-N'-ISOPROPYLGUANIDIE; 478806-77-8; IHG; AC1L9KDY; SCHEMBL564061; CHEMBL72434; 1-hydroxy-3-isopropylguanidine; SCHEMBL15424726; 1-hydroxy-2-propan-2-ylguanidine; (E)-2-hydroxy-1-isopropylguanidine; ZINC13535998; 2-hydroxy-1-(propan-2-yl)guanidine; AKOS017475215; AKOS011771464; 1-hydroxy-3-(1-methylethyl)guanidine; DB02143; ACM478806778

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 447029
CAS Number: CAS 478806-77-8
TTD Drug ID: DMIVO8P

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nitric-oxide synthase brain (NOS1)	TTZUFI5	NOS1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	6.085	5.844	5.849	5.806

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	5.20E-01	0.02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.