Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJ0W43)

Drug Name

P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid Drug Info

Synonyms

P-(2'-Iodo-5'-thenoyl)hydrotropic acid; P-(2'-IODO-5'-THENOYL)HYDROTROPIC ACID; (2S)-2-[4-(5-iodothiophene-2-carbonyl)phenyl]propanoic acid; ISF; AC1L9LAE; DB03752; (2S)-2-{4-[(5-iodothiophen-2-yl)carbonyl]phenyl}propanoic

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 447834
TTD Drug ID: DMJ0W43

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin G/H synthase 1 (COX-1)	TT8NGED	PGH1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	6.09	7.747	6.04	7.023

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	3.97E-03	0.16	0.43

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.