General Information of Drug (ID: DMJEZ62)

Drug Name
Asp-BrPmp-Leu Drug Info
Synonyms Asp-BrPmp-Leu; CHEMBL1289231; BDBM50331945
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
52949968
TTD Drug ID
DMJEZ62

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leukocyte common antigen (PTPRC) TTUS45N PTPRC_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Leukocyte common antigen (PTPRC) DTT PTPRC 6.121 6.524 4.548 6.619
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Leukocyte common antigen (PTPRC) DTT PTPRC 5.86E-05 -0.26 -0.36
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors. Bioorg Med Chem. 2010 Dec 15;18(24):8679-86.