Details of the Drug-Related molecule(s) Expression Atlas

Dazoxiben Drug Info

DAZOXIBEN; 78218-09-4; Dazoxibene; Dazoxiben [INN-Spanish]; Dazoxibenum; Dazoxibenum [INN-Latin]; Dazoxibene [INN-French]; Dazoxiben [INN:BAN]; 4-(2-(1H-Imidazol-1-yl)ethoxy)benzoic acid; UNII-09ZFC7974Q; 4-(2-imidazol-1-ylethoxy)benzoic acid; UK 37248; Benzoic acid, 4-(2-(1H-imidazol-1-yl)ethoxy)-; p-(2-Imidazol-1-ylethoxy)benzoic acid; 4-(2-(1-Imidazolyl)ethoxy)benzoesaeure; UK-37248; CHEMBL267473; 103735-00-8; 4-[2-(1H-imidazol-1-yl)ethoxy]benzoic acid; 09ZFC7974Q; AH-P 719 (9CI); NCGC00018938-03

Cross-matching ID

PubChem CID

53001

CAS Number

CAS 78218-09-4

TTD Drug ID

DMJUW8H

General Information of Drug (ID: DMJUW8H)

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thromboxane-A synthase (TBXAS1)	TTKNWZ4	THAS_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Thromboxane-A synthase (TBXAS1)	DTT	TBXAS1	5.289	4.615	4.413	3.585

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Thromboxane-A synthase (TBXAS1)	DTT	TBXAS1	6.56E-01	0.02	0.08

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Metabolic protection of the reperfused canine endocardium by the thromboxane synthetase inhibitor, dazoxiben. Prostaglandins Leukot Essent Fatty Acids. 1988 Jul;33(1):13-22.