Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMK8T61)

Drug Name

diphenyltetrahydrofuran Drug Info

Synonyms

2,2-Diphenyltetrahydrofuran; 887-15-0; 2,2-diphenyloxolane; diphenyltetrahydrofuran; NSC89761; EINECS 212-957-3; 2,2-di(phenyl)oxolane; AC1L2DIK; AC1Q1IAM; AC1Q70T2; GTPL2498; SCHEMBL1569110; Furan,tetrahydro-2,2-diphenyl-; CTK5G1253; DTXSID70237245; Furan, tetrahydro-2,2-diphenyl-; ZINC1575610; NSC-89761; AKOS024323254; MCULE-6052973560; X4640

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 70175
CAS Number: CAS 887-15-0
TTD Drug ID: DMK8T61

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Transient receptor potential cation channel V3 (TRPV3)	TT946IA	TRPV3_HUMAN	Blocker (channel blocker)	[2]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Transient receptor potential cation channel V3 (TRPV3)	DTT	TRPV3	7.58E-01	5.28E-03	0.05

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2498).
2	Biphasic currents evoked by chemical or thermal activation of the heat-gated ion channel, TRPV3. J Biol Chem. 2005 Apr 22;280(16):15928-41.