Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DML8BT7)

• Drug Name: PAS219 Drug Info
• Synonyms: PAS219; CHEMBL24811; CYCLOHEXYLMETHYL 2-FORMYLPHENYL HYDROGEN PHOSPHATE; Fragment 15; AC1NR9QB; BDBM14685; DB03114; cyclohexylmethoxy(2-formylphenoxy)phosphinic acid; (cyclohexylmethoxy)(2-formylphenoxy)phosphinic acid; cyclohexylmethyl (2-formylphenyl) hydrogen phosphate; Phosphoric acid (cyclohexylmethyl)2-formylphenyl ester; Phosphoric acid cyclohexylmethyl ester 2-formyl-phenyl ester

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5287461
  TTD Drug ID: DML8BT7

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Proto-oncogene c-Src (SRC)	TT6PKBN	SRC_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Proto-oncogene c-Src (SRC)	DTT	SRC	2.907	3.35	3.498	4.75

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Proto-oncogene c-Src (SRC)	DTT	SRC	6.45E-01	-0.08	-0.58
Proto-oncogene c-Src (SRC)	DTT	SRC	2.08E-03	-0.52	-1.62

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.