Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMLYHUN)

Drug Name

JWH-208 Drug Info

Synonyms

JWH-208; BDU1DA9SRY; UNII-BDU1DA9SRY; CHEMBL187354; JWH 251 4-methylphenyl isomer; 864445-41-0; GSVYYNBRAJBCQS-UHFFFAOYSA-N; ZINC28462048; BDBM50170351; 1-(1-pentyl-1H-indol-3-yl)-2-p-tolylethanone; 1-(1-Pentyl-1H-indol-3-yl)-2-p-tolyl-ethanone; 2-(4-Methylphenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone; Ethanone, 2-(4-methylphenyl)-1-(1-pentyl-1H-indol-3-yl)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 44397464
CAS Number: CAS 864445-41-0
TTD Drug ID: DMLYHUN

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cannabinoid receptor 2 (CB2)	TTMSFAW	CNR2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Cannabinoid receptor 2 (CB2)	DTT	CNR2	7.037	6.733	6.944	7.163

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Cannabinoid receptor 2 (CB2)	DTT	CNR2	3.82E-02	-0.43	-1.18

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4110-3.