Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMM4ZKU)

Drug Name

ZAPOTIN Drug Info

Synonyms

Zapotin; 14813-19-5; CHEMBL375582; 5,6,2',6'-tetramethoxyflavone; 2-(2,6-dimethoxyphenyl)-5,6-dimethoxychromen-4-one; Flavone, 2',5,6,6'-tetramethoxy-; AC1LCGQ2; SCHEMBL3307703; 2',6',5,6-Tetramethoxyflavon; DTXSID80348078; 2-(2,6-Dimethoxyphenyl)-5,6-dimethoxy-4H-chromen-4-one; PBQMALAAFQMDSP-UHFFFAOYSA-N; 2',5,6,6'-Tetramethoxyflavone; MolPort-005-945-165; 4H-1-Benzopyran-4-one, 2-(2,6-dimethoxyphenyl)-5,6-dimethoxy-; 5,6,2'',6''-tetramethoxyflavone; ZINC14756841; LMPK12110091; Flavone,2',5,6,6'-tetramethoxy-; BDBM50202558

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 629965
CAS Number: CAS 14813-19-5
TTD Drug ID: DMM4ZKU

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ornithine decarboxylase (ODC1)	TTUMGNO	DCOR_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Ornithine decarboxylase (ODC1)	DTT	ODC1	9.956	8.598	9.482	8.752

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Ornithine decarboxylase (ODC1)	DTT	ODC1	5.20E-35	1.58	2.43

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. J Med Chem. 2007 Jan 25;50(2):350-5.