Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMM8TE0)

Drug Name

(R)-N-benzyl-4-(pyrrolidin-2-ylmethoxy)aniline Drug Info

Synonyms

N-Benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline; N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline; CHEMBL570775; SCHEMBL4314176; HITMFLNAOQIZSN-QGZVFWFLSA-N; BDBM50294163; DB07260

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 44129620
TTD Drug ID: DMM8TE0

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leukotriene A-4 hydrolase (LTA4H)	TTXZEAJ	LKHA4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	7.338	7.827	8.134	8.612

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	1.31E-48	-1.22	-2.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.