Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN320E)

Drug Name
A-558693 Drug Info
Synonyms A-705239; A-705253; Calpain inhibitors (neurological disorders); Calpain inhibitors, Knoll; Calpain inhibitors (neurological disorders), Abbott
Indication
Disease Entry ICD 11 Status REF
Neurological disorder 6B60 Investigative [1]
Cross-matching ID
TTD Drug ID
DMN320E

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calpain-2 (CAPN2) TTG5QB7 CAN2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Neurological disorder
ICD Disease Classification 6B60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Calpain-2 (CAPN2) DTT CAPN2 5.15E-14 0.35 1.04
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2336).