Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN53R0)

Drug Name
Pyrazole derivative 62 Drug Info
Synonyms PMID26394986-Compound-23
Cross-matching ID
PubChem CID
72543768
TTD Drug ID
DMN53R0

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Signal transducer and activator of transcription 3 (STAT3) TTH8FZW STAT3_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Signal transducer and activator of transcription 3 (STAT3) DTT STAT3 9.537 8.097 9.732 8.128
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Signal transducer and activator of transcription 3 (STAT3) DTT STAT3 6.50E-03 -0.12 -0.21
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A STAT inhibitor patent review: progress since 2011.Expert Opin Ther Pat. 2015;25(12):1397-421.