Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN5YOR)

Drug Name

C-(9H-Xanthen-9-yl)-methylamine Drug Info

Synonyms

100866-28-2; XANTHENE-9-METHYLAMINE; 9H-Xanthene-9-methanamine; CHEMBL155276; 1-(9H-Xanthen-9-yl)methanamine; C-(9H-Xanthen-9-yl)-methylamine; 9-aminomethylxanthene; ACMC-20m3ww; 9-AMINOMETHYL XANTHENE; SCHEMBL4667689; CTK0H2362; DTXSID20576237; VYDDHEPARBFMGU-UHFFFAOYSA-N; ZINC21984468; BDBM50097214; AKOS015152152; (9H-XANTHEN-9-YL)METHANAMINE; AB24946

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 15645577
CAS Number: CAS 100866-28-2
TTD Drug ID: DMN5YOR

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 2A receptor (HTR2A)	TTJQOD7	5HT2A_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 2A receptor (HTR2A)	DTT	HTR2A	4.84	4.904	4.652	4.129

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 2A receptor (HTR2A)	DTT	HTR2A	1.68E-01	-0.3	-0.14
5-HT 2A receptor (HTR2A)	DTT	HTR2A	5.59E-01	0.15	0.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Exploring the relationship between binding modes of 9-(aminomethyl)-9,10-dihydroanthracene and cyproheptadine analogues at the 5-HT2A serotonin rec... Bioorg Med Chem Lett. 2001 Feb 26;11(4):563-6.