Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN5Z0F)

Drug Name
Acetyl-Pro-Ala-Pro-Ala-trifluoro methane Drug Info
Synonyms CHEMBL130718; Acetyl-Pro-Ala-Pro-Ala-trifluoro methane; BDBM50014740
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44353385
ChEBI ID
CHEMBL130718
TTD Drug ID
DMN5Z0F

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pancreatic elastase 1 (CELA1) TT3NKIB CELA1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Pancreatic elastase 1 (CELA1) DTT CELA1 8.56E-02 0.06 0.25
Pancreatic elastase 1 (CELA1) DTT CELA1 3.82E-02 0.19 0.7
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, ... J Med Chem. 1990 Jan;33(1):394-407.