General Information of Drug (ID: DMNM8VY)

Drug Name
4-(piperazin-1-yl)furo[3,2-c]pyridine Drug Info
Synonyms
4-(piperazin-1-yl)furo[3,2-c]pyridine; 81078-84-4; 4-PIPERAZIN-1-YL-FURO[3,2-C]PYRIDINE; 1-{furo[3,2-c]pyridin-4-yl}piperazine; CHEMBL595555; Furo[3,2-c]pyridine, 4-(1-piperazinyl)-; AK-76639; CHEMBL543969; PubChem17312; AC1MDRY3; SCHEMBL1026755; KS-00000EXO; CTK5E8449; DTXSID10383432; MolPort-000-145-249; LUIZVTKJWSGSPA-UHFFFAOYSA-N; ZINC4287704; 4-piperazinylfurano[3,2-c]pyridine; ANW-49259; BDBM50016972; SBB093149; 4-piperazin-1-ylfuro[3,2-c]pyridine; AKOS015919593; FS-3269; 1-(4-furo[3,2-c]pyridinyl)piperazine
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2794808
CAS Number
CAS 81078-84-4
TTD Drug ID
DMNM8VY

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 2C receptor (HTR2C) TTWJBZ5 5HT2C_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
5-HT 2C receptor (HTR2C) DTT HTR2C 4.233 3.329 3.843 3.888
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 2C receptor (HTR2C) DTT HTR2C 1.02E-02 -0.45 -0.37
5-HT 2C receptor (HTR2C) DTT HTR2C 2.27E-01 0.27 0.6
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity. Bioorg Med Chem Lett. 2010 Jan 1;20(1):266-71.