Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMO8LPZ)

• Drug Name: Beta-Hydroxy Aspartic Acid Drug Info
• Synonyms: 71653-06-0; 2-Amino-3-hydroxysuccinic Acid; Malic acid, 3-amino-; 2-amino-3-hydroxybutanedioic acid; d,l-threo-3-HYDROXYASPARTIC ACID; NSC618260; 1860-87-3; CHEBI:83981; 2-amino-3-hydroxy-butanedioic acid; 3-Hydroxy-DL-aspartic acid; Aspartic acid, 3-hydroxy-; D,L-Threo-b-hydroxyaspartic acid; DL-threo-3-Hydroxyaspartic acid; 3-aminomalic acid; EINECS 275-771-1

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5425
  ChEBI ID: CHEBI:83981
  CAS Number: CAS 71653-06-0
  TTD Drug ID: DMO8LPZ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Coagulation factor Xa (F10)	TTCIHJA	FA10_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Coagulation factor Xa (F10)	DTT	F10	7.763	4.672	3.248	4.609

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Coagulation factor Xa (F10)	DTT	F10	4.84E-02	-0.28	-0.9

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.