Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMOCYDU)

Drug Name

5-chloro-1H-indazole Drug Info

Synonyms

5-Chloro-1H-indazole; 698-26-0; 1H-Indazole, 5-chloro-; 5-Chloroindazole; 5-CHLORO INDAZOLE; EINECS 211-812-1; NSC 78434; BRN 0003260; CHEMBL246746; FVNCILPDWNBPLK-UHFFFAOYSA-N; AK-23822; 5-chloro-indazole; 2H-Indazole, 5-chloro-; NSC78434; 5-chloro-2H-indazole; AC1L2CF8; 5-23-06-00175 (Beilstein Handbook Reference); 5-CHLORO(1H)INDAZOLE; SCHEMBL3540025; SCHEMBL16523221; CTK2F6769; DTXSID70220091; MolPort-000-002-983; 5-Chloro-1H-indazole, AldrichCPR; ZX-CM006597; ZX-AT013670; ZINC4876880; BCP00023; ACT10091; FCH837623; BDBM50209242

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 69681
CAS Number: CAS 698-26-0
TTD Drug ID: DMOCYDU

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nitric-oxide synthase brain (NOS1)	TTZUFI5	NOS1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	6.085	5.844	5.849	5.806

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	5.20E-01	0.02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80.