Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMOPMNC)

Drug Name

(5-methoxy-1H-indol-3-yl)methanamine Drug Info

Synonyms

(5-methoxy-1H-indol-3-yl)methanamine; 60523-82-2; 5-Methoxy-1h-indol-3-methylamine; 3-(AMINOMETHYL)-5-METHOXYINDOLE; CHEMBL1276050; 5-METHOXYINDOLE-3-METHYLAMINE; SCHEMBL3976318; CTK5B1636; DTXSID20563182; MolPort-006-831-850; ZX-AN081076; ALBB-030269; FCH853008; BDBM50330861; 9026AB; ZINC20269183; AKOS005214650; MB03907; CM-1862; SC-45599; KB-43524; AJ-76727; AK112525; ST2402466; DB-012273; AX8104451; FT-0691098; 4CH-017193; 1-(5-METHOXY-1H-INDOL-3-YL)METHANAMINE

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 14702424
CAS Number: CAS 60523-82-2
TTD Drug ID: DMOPMNC

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 2B receptor (HTR2B)	TT0K1SC	5HT2B_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 2B receptor (HTR2B)	DTT	HTR2B	0.485	3.536	0.379	4.667

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 2B receptor (HTR2B)	DTT	HTR2B	2.08E-01	-0.05	-0.23

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify no... J Med Chem. 2010 Nov 11;53(21):7573-86.