Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMOYADT)

Drug Name

AF150(S) Drug Info

Synonyms

AF150(S); SCHEMBL1328277; AF-150S; VGGGBQVTSUMURJ-UHFFFAOYSA-N; AF 150(S); AF-150(S); L007073; 1-methylpiperidine-4-spiro-(2'-methylthiazoline); 2,8-dimethyl-1-thia-3,8-diaza-spiro[4.5]dec-2-ene; 1-Thia-3,8-diazaspiro(4.5)dec-2-ene, 2,8-dimethyl-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 10176415
CAS Number: CAS 138300-72-8
TTD Drug ID: DMOYADT

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Muscarinic acetylcholine receptor M1 (CHRM1)	TTZ9SOR	ACM1_HUMAN	Agonist	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Muscarinic acetylcholine receptor M1 (CHRM1)	DTT	CHRM1	5.59E-01	0.19	0.41

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	M1 muscarinic agonists target major hallmarks of Alzheimer's disease--an update. Curr Alzheimer Res. 2007 Dec;4(5):577-80.