Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMP6G0P)

Drug Name
TT-00920 Drug Info
Indication
Disease Entry ICD 11 Status REF
Heart failure BD10-BD13 Phase 1 [1]
Sickle-cell disorder 3A51 Preclinical [1]
Cross-matching ID
TTD Drug ID
DMP6G0P

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 9 (PDE9) TTZOEBC PDE9A_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Phosphodiesterase 9 (PDE9) DTT PDE9A 1.807 8.131 3.263 2.7
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Heart failure
ICD Disease Classification BD10-BD13
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Phosphodiesterase 9 (PDE9) DTT PDE9A 8.73E-03 0.07 0.36
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of TransThera Biosciences