Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPEV2W)

• Drug Name: (R)-3-Prop-2-ynylamino-indan-5-ol Drug Info
• Synonyms: 5-Hydroxy-N-propargyl-1(R)-aminoindan; 5-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN; CHEMBL371428; 6-hydroxy-n-propargyl-1(r)-aminoindan; (3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL; (3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-ol; R-HPAI; AC1NRD0T; Aminoindan deriv (R)39u; SCHEMBL4188273; BDBM10799; 1H-Inden-5-ol, 2,3-dihydro-3-(2-propyn-1-ylamino)-, (3R)-; DB04307; 479206-03-6; 5-Hydroxy-N-Propargyl-1(R)-Aminoindan

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5289289
  TTD Drug ID: DMPEV2W

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type B (MAO-B)	TTGP7BY	AOFB_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type B (MAO-B)	DTT	MAOB	9.367	6.907	8.237	8.409

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type B (MAO-B)	DTT	MAOB	2.65E-02	1.12E-02	0.07

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.