General Information of Drug (ID: DMPH63G)

Drug Name
2-(2-Methylpropanoyl)-1,3,5-benzenetriol Drug Info
Synonyms
Phlorisobutyrophenone; 35458-21-0; 2-(2-Methylpropanoyl)-1,3,5-benzenetriol; 1-Propanone, 2-methyl-1-(2,4,6-trihydroxyphenyl)-; CHEMBL20038; 2-methyl-1-(2,4,6-trihydroxyphenyl)propan-1-one; 2-Methyl-1-(2,4,6-trihydroxyphenyl)-1-propanone; phlorisobutanophenone; phloroisobutyrophenone; AC1NS0BJ; 2-isobutyrylphloroglucinol; 2-isobutanoylphloroglucinol; SCHEMBL2150396; CTK1B6928; DTXSID60416108; MolPort-022-379-188; BNEBXEZRBLYBCZ-UHFFFAOYSA-N; CHEBI:133419; ZINC13650343; BDBM50005639; 1-isobutyryl-2,4,6-trihydroxybenzene
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5326317
ChEBI ID
CHEBI:133419
CAS Number
CAS 35458-21-0
TTD Drug ID
DMPH63G

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin G/H synthase 1 (COX-1) TT8NGED PGH1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Prostaglandin G/H synthase 1 (COX-1) DTT PTGS1 6.09 7.747 6.04 7.023
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostaglandin G/H synthase 1 (COX-1) DTT PTGS1 3.97E-03 0.16 0.43
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Anti-inflammatory acylphloroglucinol derivatives from Hops (Humulus lupulus). J Nat Prod. 2005 Oct;68(10):1545-8.