Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPRNQL)

Drug Name
BQ610 Drug Info
Synonyms
BQ-610; 141595-53-1; BQ 610; AZEPANE-1-CARBONYL-LEU-D-TRP(FOR)-D-TRP-OH; BQ610; Hexahydroazepinocarbonyl-leu-D-trp(cho)-D-trp; Hexahydroazepinocarbonyl-leucyl-tryptophyl(cho)-tryptophan; AC1L3XIP; SCHEMBL2678706; CTK8F0466; DTXSID20161768; ZINC72190207; D-Tryptophan, N-(1-formyl-N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-D-tryptophyl)-; RT-011809; J-007520; (R)-2-((R)-2-((S)-2-(azepane-1-carboxamido)-4-methylpentanamido)-3-(1-formyl-1H-indol-3-yl)propanamido)-3-(1H-indol-3-yl)propanoic acid
Cross-matching ID
PubChem CID
123905
CAS Number
CAS 141595-53-1
TTD Drug ID
DMPRNQL

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Endothelin A receptor (EDNRA) TTKRD0G EDNRA_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Endothelin A receptor (EDNRA) DTT EDNRA 3.776 4.505 5.121 3.536
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Endothelin A receptor (EDNRA) DTT EDNRA 3.19E-05 -2.69 -1.71
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Human optic nerve head astrocytes as a target for endothelin-1. Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2704-13.