Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMQYJIR)

Drug Name
Macimorelin Drug Info
Synonyms Solorel; AEZS-130; ARD-07; ARD-0705; EP-01572; EP-1572; JMV-1843
Indication
Disease Entry ICD 11 Status REF
Growth hormone deficiency 5A61.3 Approved [1]
Somatotropin deficiency 5A61.0 Approved [2]
Cross-matching ID
PubChem CID
9804938
CAS Number
CAS 381231-18-1
TTD Drug ID
DMQYJIR
ACDINA Drug ID
D01233

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Growth hormone secretagogue receptor 1 (GHSR) TTWDC17 GHSR_HUMAN Agonist [3]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Growth hormone secretagogue receptor 1 (GHSR) DTT GHSR 2.609 4.104 4.797 1.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Growth hormone deficiency
ICD Disease Classification 5A61.3
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Growth hormone secretagogue receptor 1 (GHSR) DTT GHSR 4.56E-01 -0.14 -0.74
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85.
3 National Cancer Institute Drug Dictionary (drug id 735530).