Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMR97FU)

Drug Name

1-Benzo[b]thiophen-2-yl-cyclohexylamine Drug Info

Synonyms

Cyclohexanamine, 1-benzo[b]thien-2-yl-; CHEMBL18556; 143603-26-3; NSC708121; ACMC-20bbzv; 1-Benzo[b]thiophen-2-yl-cyclohexylamine; AC1L9GJR; SCHEMBL7095248; CTK0B4318; DTXSID80327969; HYVMNAZTYJDWIZ-UHFFFAOYSA-N; ZINC1657638; BDBM50040190; AKOS030613260; NSC-708121; 1-(1-Benzothien-2-yl)cyclohexanamine #; Thionaphthene, 2-[1-aminocyclohex-1-yl]-; 1-(1-benzothiophen-2-yl)cyclohexan-1-amine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 398415
CAS Number: CAS 143603-26-3
TTD Drug ID: DMR97FU

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Dopamine transporter (DAT)	TTVBI8W	SC6A3_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Dopamine transporter (DAT)	DTT	SLC6A3	4	2.609	5.233	3.7

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Dopamine transporter (DAT)	DTT	SLC6A3	1.08E-03	-3.08	-1.99

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-bin... J Med Chem. 1993 Apr 30;36(9):1188-93.