General Information of Drug (ID: DMRDF8Z)

Drug Name
Piridronic acid Drug Info
Synonyms
Piridronic acid; UNII-ADD4H8T3K9; ADD4H8T3K9; CHEMBL99369; 75755-07-6; NE-97221; (1-phosphono-2-pyridin-2-ylethyl)phosphonic acid; Acido piridronico; Acide piridronique; Acidum piridronicum; Piridronic acid [INN]; NE 97221; Acido piridronico [Spanish]; Acidum piridronicum [Latin]; Acide piridronique [French]; AC1L1NEH; AC1Q7DKX; (2-(2-Pyridyl)ethylidene)diphosphonic acid; SCHEMBL223779; GTPL3183; DTXSID50226652; ZINC1999562; BDBM50373096; NE97221; 2-(2-Pyridyl)ethylidine-1,1-bisphosphonate; Phosphonic acid, (2-(2-pyridinyl)ethylide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
57637
CAS Number
CAS 75755-07-6
TTD Drug ID
DMRDF8Z

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Geranyltranstransferase (FDPS) TTIKWV4 FPPS_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Geranyltranstransferase (FDPS) DTT FDPS 7.06E-03 -0.73 -2.57
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3183).
2 Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of hu... J Med Chem. 2008 Apr 10;51(7):2187-95.