Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMRNGV0)

Drug Name

N*6*-Benzyl-quinazoline-2,4,6-triamine Drug Info

Synonyms

CHEMBL115474; N*6*-Benzyl-quinazoline-2,4,6-triamine; AC1LA5GO; ZINC5974540; BDBM50066486; N6-benzylquinazoline-2,4,6-triamine; 6-N-benzylquinazoline-2,4,6-triamine; 2,4-diamino-6-(benzylamino)quinazoline; 6-(Benzylamino)-2,4-quinazolinediamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 462120
TTD Drug ID: DMRNGV0

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Polypeptide deformylase (PDF)	TT9SL3Q	DEFM_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Polypeptide deformylase (PDF)	DTT	PDF	8.87E-16	-0.54	-0.86

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	CoMFA and CoMSIA analyses of Pneumocystis carinii dihydrofolate reductase, Toxoplasma gondii dihydrofolate reductase, and rat liver dihydrofolate r... J Med Chem. 2005 Mar 10;48(5):1448-69.