Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMSGIXK)

Drug Name

BQCA Drug Info

Synonyms

TBPB; Benzyl quinolone carboxylic acid; M1 muscarinic acetylcholine receptor agonist (Alzherimer's disease); M1mAChRs (neurological disorder), Merck & Co; M1 muscarinic acetylcholine receptor agonist (Alzherimer's disease), Merck & Co

Indication

Disease Entry	ICD 11	Status	REF
Neurological disorder	6B60	Investigative	[1]

Cross-matching ID

PubChem CID: 1476756
CAS Number: CAS 338747-41-4
TTD Drug ID: DMSGIXK

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Muscarinic acetylcholine receptor M1 (CHRM1)	TTZ9SOR	ACM1_HUMAN	Agonist	[2]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Neurological disorder

ICD Disease Classification

6B60

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Muscarinic acetylcholine receptor M1 (CHRM1)	DTT	CHRM1	5.59E-01	0.19	0.41

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5436).
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5436).