Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMSMVK4)

Drug Name
Ac-WVTHRLAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
91935701
ChEBI ID
CHEMBL503773
TTD Drug ID
DMSMVK4

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcitonin gene-related peptide 1 (CALCA) TTVSFJW CALCA_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Calcitonin gene-related peptide 1 (CALCA) DTT CALCA 5.221 2.818 4.501 4.647
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Calcitonin gene-related peptide 1 (CALCA) DTT CALCA 1.80E-07 -0.32 -0.62
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor. J Med Chem. 2008 Dec 25;51(24):7889-97.