Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMTEQU8)

Drug Name

2-(4-Methoxy-phenyl)-1H-indole-3-carbaldehyde Drug Info

Synonyms

2-(4-methoxyphenyl)-1H-indole-3-carbaldehyde; 76195-80-7; AC1MY4K3; CHEMBL144222; SCHEMBL15332438; CTK2G8075; DTXSID90396949; MolPort-006-701-191; IAL-1620; ZX-BK002979; ZINC3675784; KM5032; STK894724; BBL022005; AKOS005143919; MCULE-1940549514; 1H-Indole-3-carboxaldehyde, 2-(4-methoxyphenyl)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3826063
CAS Number: CAS 76195-80-7
TTD Drug ID: DMTEQU8

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tubulin (TUB)	TTML2WA	NOUNIPROTAC	Inhibitor	[1]
Tubulin beta (TUBB)	TTYFKSZ	NOUNIPROTAC	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tubulin (TUB)	DTT	TUB	7.743	8.411	8.625	8.347

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tubulin (TUB)	DTT	NO-GeName	7.94E-02	0.35	0.43

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization. J Med Chem. 1998 Dec 3;41(25):4965-72.