Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMTFNGM)

Drug Name
Sulfonamide derivative 16 Drug Info
Synonyms PMID29886770-Compound-Figure6
Cross-matching ID
TTD Drug ID
DMTFNGM

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase 6 (HDAC6) TT5ZKDI HDAC6_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Histone deacetylase 6 (HDAC6) DTT HDAC6 5.35 3.365 3.963 4.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Histone deacetylase 6 (HDAC6) DTT HDAC6 6.91E-02 0.27 0.79
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Sulfonamide inhibitors: a patent review 2013-present.Expert Opin Ther Pat. 2018 Jul;28(7):541-549.