Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMTX0ZJ)

Drug Name
PMID19743866C51 Drug Info
Synonyms Ac-RLTbaLAR-H; GTPL8653; BDBM50314023
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
46883596
ChEBI ID
CHEMBL1089597
TTD Drug ID
DMTX0ZJ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement factor B (CFB) TTA0P7K CFAB_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Complement factor B (CFB) DTT CFB 10.419 4.895 7.235 6.78
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement factor B (CFB) DTT CFB 1.63E-02 0.07 0.13
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Structure-activity relationships for substrate-based inhibitors of human complement factor B. J Med Chem. 2009 Oct 8;52(19):6042-52.