Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMU5H4K)

• Drug Name: RU78783 Drug Info
• Synonyms: RU78783; (PHENYL-PHOSPHONO-METHYL)-PHOSPHONIC ACID; (phenylmethanediyl)bis(phosphonic acid); [phenyl(phosphono)methyl]phosphonic acid; Fragment 8; 1o4r; benzylidenebisphosphonic acid; AC1L9KY6; SCHEMBL4094661; phenyl methane diphosphonic acid; CHEMBL148732; Phenylmethylenebisphosphonic acid; BDBM14678; FRLTXWJJMCIUNT-UHFFFAOYSA-N; phenyl(phosphono)methylphosphonic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 447537
  TTD Drug ID: DMU5H4K

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Proto-oncogene c-Src (SRC)	TT6PKBN	SRC_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Proto-oncogene c-Src (SRC)	DTT	SRC	2.907	3.35	3.498	4.75

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Proto-oncogene c-Src (SRC)	DTT	SRC	6.45E-01	-0.08	-0.58
Proto-oncogene c-Src (SRC)	DTT	SRC	2.08E-03	-0.52	-1.62

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.