Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUE0D6)

Drug Name

2-(1,1'-Biphenyl-4-Yl)Propanoic Acid Drug Info

Synonyms

alpha-Methyl-4-biphenylacetic acid; 6341-72-6; BPPA; NSC 16300; Ly 71130; 2-(p-Biphenyl)propionic acid; 2-(4-phenylphenyl)propanoic acid; 4-BIPHENYLACETIC ACID, alpha-METHYL-; CHEMBL317434; 2-Biphenyl-4-yl-propionic acid; Biprofen; 2-(4-Biphenylyl)propionic Acid; (1,1'-Biphenyl)-4-acetic acid, alpha-methyl-; 2-[1,1'-biphenyl]-4-ylpropanoic acid; [1,1'-Biphenyl]-4-aceticacid, a-methyl-; [1,1'-Biphenyl]-4-acetic acid, alpha-methyl-; alpha-Methyl-4-biphenyl-acetic acid; p-Phenylhydratropic Acid; 2-(4-Biphenyl)propionic acid,; Alpha-Methyl-4-biphenyl-acetic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 448006
CAS Number: CAS 10532-14-6
TTD Drug ID: DMUE0D6

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin G/H synthase 1 (COX-1)	TT8NGED	PGH1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	6.09	7.747	6.04	7.023

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin G/H synthase 1 (COX-1)	DTT	PTGS1	3.97E-03	0.16	0.43

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.