Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMVO0LU)

Drug Name
131I-81C6 Drug Info
Synonyms Neuradiab; MAb-81C6; Iodine-131-81C6; Astatine-211-MAb-81C6; Iodine-131-MAb-81C6; Iodine-131-ch-81C6; Iodine-131-ch-81C6-F(ab)2; 211At-MAb-81C6
Indication
Disease Entry ICD 11 Status REF
Brain cancer 2A00 Terminated [1]
Cross-matching ID
TTD Drug ID
DMVO0LU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tenascin (TNC) TTUCPMY TENA_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tenascin (TNC) DTT TNC 4.365 6.758 6.7 6.126
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Brain cancer
ICD Disease Classification 2A00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tenascin (TNC) DTT TNC 2.41E-162 2.68 3.01
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Human IgG2 constant region enhances in vivo stability of anti-tenascin antibody 81C6 compared with its murine parent. Clin Cancer Res. 1998 Oct;4(10):2495-502.