Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXCSVH)

• Drug Name: Oleic acid anilide Drug Info
• Synonyms: Oleanilide; Oleic acid anilide; Oleoylanilide; Oleylanilide; cis-9-Octadecenanilide; Oleyl anilide; (Z)-N-Phenyl-9-octadeceneamide; 5429-85-6; N-Phenyl-9Z-octadecenamide; (Z)-N-phenyl-9-octadecenamide; CHEBI:53721; EINECS 226-584-9; NSC 14233; 9-Octadecenamide, N-phenyl-, (Z)-; BRN 3533033; CHEMBL15611; (9Z)-N-phenyloctadec-9-enamide; Oleic anilide; C24H39NO; Oleanilide (7CI); AC1NS5WI; Epitope ID:117134; 2-12-00-00150 (Beilstein Handbook Reference); SCHEMBL4143902; (Z)-N-phenyloctadec-9-enamide; Octadec-9-enoic acid phenylamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5354590
  ChEBI ID: CHEBI:53721
  CAS Number: CAS 5429-85-6
  TTD Drug ID: DMXCSVH

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Liver carboxylesterase (CES1)	TTMF541	EST1_HUMAN	Inhibitor	[2]
SOAT2 messenger RNA (SOAT2 mRNA)	TTAK0IN	SOAT2_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Liver carboxylesterase (CES1)	DTT	CES1	12.04	6.525	5.311	5.909
SOAT2 messenger RNA (SOAT2 mRNA)	DTT	SOAT2	3.807	4.848	3.689	6.585

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Liver carboxylesterase (CES1)	DTT	CES1	3.82E-08	1.86	1.9

References

• [1] Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5580-3.
• [2] Phenolic compounds from the roots of Lindera fruticosa. J Nat Prod. 2006 May;69(5):853-5.