Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMYK6OU)

Drug Name
RQ-00310941 Drug Info
Synonyms RQ-00202065; 5-HT 2b antagonists (oral, IBS), RaQualia; 5-HT 2b antagonists (oral, irritable bowel syndrome), RaQualia
Indication
Disease Entry ICD 11 Status REF
Irritable bowel syndrome DD91.0 Investigative [1]
Cross-matching ID
PubChem CID
46208154
TTD Drug ID
DMYK6OU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 2B receptor (HTR2B) TT0K1SC 5HT2B_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
5-HT 2B receptor (HTR2B) DTT HTR2B 0.485 3.536 0.379 4.667
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Irritable bowel syndrome
ICD Disease Classification DD91.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 2B receptor (HTR2B) DTT HTR2B 2.08E-01 -0.05 -0.23
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 7).