General Information of Drug (ID: DMYSNQO)

Drug Name
7-acetonyloxy-3-acetylamino-8-methoxycoumarin Drug Info
Synonyms CHEMBL201250; 7-acetonyloxy-3-acetylamino-8-methoxycoumarin; CTK6J4706; BDBM50181853; AKOS015965518; N-[8-Methoxy-2-oxo-7-(2-oxo-propoxy; N-(8-methoxy-2-oxo-7-(2-oxopropoxy)-2H-chromen-3-yl)acetamide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
11623661
TTD Drug ID
DMYSNQO

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type A (MAO-A) TT3WG5C AOFA_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Monoamine oxidase type A (MAO-A) DTT MAOA 7.207 8.159 9.043 7.711
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type A (MAO-A) DTT MAOA 8.14E-01 0.05 0.1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins. J Med Chem. 2006 Feb 9;49(3):1149-56.