Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZ1TNM)

Drug Name

4-(3'-furyl)-aniline Drug Info

Synonyms

Benzenamine, 4-(3-furanyl)-; 4-(furan-3-yl)aniline; 4-furan-3-yl-phenylamine; CHEMBL374967; SCHEMBL1016530; NSKKXDBWURWAOW-UHFFFAOYSA-N; AKOS013265082

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 44420988
CAS Number: CAS 936249-47-7
TTD Drug ID: DMZ1TNM

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Norepinephrine transporter (NET)	TTAWNKZ	SC6A2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Norepinephrine transporter (NET)	DTT	SLC6A2	2.459	3.426	3.322	3.35

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Norepinephrine transporter (NET)	DTT	SLC6A2	7.05E-01	7.02E-03	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Designing active template molecules by combining computational de novo design and human chemist's expertise. J Med Chem. 2007 Apr 19;50(8):1925-32.