Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZKO14)

Drug Name

7-Methyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine Drug Info

Synonyms

TCMDC-139863; 7-Methyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine; CHEMBL174414; 7-methylpyrrolo[3,2-f]quinazoline-1,3-diamine; AC1LAG62; SCHEMBL11612134; 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-methyl-; WSISEVQVCUARDZ-UHFFFAOYSA-N; BDBM50049900; 65796-02-3

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 467889
TTD Drug ID: DMZKO14

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Polypeptide deformylase (PDF)	TT9SL3Q	DEFM_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Polypeptide deformylase (PDF)	DTT	PDF	8.87E-16	-0.54	-0.86

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines w... J Med Chem. 1996 Feb 16;39(4):892-903.