Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM049IX)

Drug Name

CDRI-97/78 Drug Info

Synonyms

Antimalarial compound, CDRI/IPCA labs

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Plasmodial phospholipid metabolism (PPP metab)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SAR97276	DMG9MN2	Malaria	1F40-1F45	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasmodial phospholipid metabolism (PPP metab)	TTQ2GJ0	NOUNIPROTAC	Modulator	[2]

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References

1	Simultaneous quantification of proposed anti-malarial combination comprising of lumefantrine and CDRI 97-78 in rat plasma using the HPLC-ESI-MS/MS method: application to drug interaction study. MalarJ. 2015 Apr 22;14:172.
2	Single Ascending Dose Safety and Pharmacokinetics of CDRI-97/78: First-in-Human Study of a Novel Antimalarial Drug. Malar Res Treat. 2014;2014:372521.
3	Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate. Br J Pharmacol. 2012 August; 166(8): 2263-2276.