Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM06GDC)

Drug Name

T2c-001 Drug Info

Synonyms

T2c-001-AMI; T2c-001-CHD; T2c-001-DCM; T2c-001-SW; Autologous bone marrow-derived endothelial progenitor cell therapy, Goethe University/t2cure; Autologous endothelial progenitor cells (myocardial infarction), Goethe University/t2cure; Endothelial progenitor cell therapy (ischemia), Goethe University/t2cure

Indication

Disease Entry	ICD 11	Status	REF
Congestive heart failure	BD10	Phase 2	[1]

Cross-matching ID

TTD Drug ID: DM06GDC

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting T-cells (T-cells)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ATG-Fresenius S	DM4VJ5Q	Transplant rejection	NE84	Phase 3	[3]
DiabeCell	DMK6FYR	Insulin-dependent diabetes	5A10	Phase 2	[2]
TVI-Kidney-1	DMGYSZ0	Renal cell carcinoma	2C90	Phase 2	[4]
Baltaleucel-T	DM3WCL4	Diffuse large B-cell lymphoma	2A81	Phase 2	[5]
BPX-501	DMIMA4V	Acute lymphoblastic leukaemia	2A85	Phase 1/2	[5]
AX-024	DMRQ32K	Multiple sclerosis	8A40	Phase 1	[6]
RTL-1000	DM1B4CQ	Multiple sclerosis	8A40	Phase 1	[7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
T-cells (T-cells)	TTXQYT6	NOUNIPROTAC	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT01693042) Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-derived Mononuclear Cells on Mortality in Patients With Chronic Post-infarction Heart Failure. U.S. National Institutes of Health.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3	Clinical pipeline report, company report or official report of Neovii Biotech.
4	Clinical pipeline report, company report or official report of TVAX Biomedical.
5	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
7	RTL THERAPY FOR MULTIPLE SCLEROSIS: A Phase I Clinical Study. J Neuroimmunol. 2011 February; 231(1-2): 7-14.