Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0KXN4)

Drug Name

alpha-oxoadipic acid Drug Info

Synonyms

alpha-ketoadipic acid; 2-ketoadipate; 2-oxoadipate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTP

Drug Status:

Investigative Drug(s)

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Drug(s) Transported By Mitochondrial 2-oxodicarboxylate carrier (SLC25A21)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
alpha-ketoglutaric acid	DM5LFYN	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21)	DT2UQYR	ODC_HUMAN	Substrate	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4657).
2	Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy-like disease. Genet Med. 2018 Oct;20(10):1224-1235.