Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0LRU9)

Drug Name
Fendrix Drug Info
Synonyms
Fendrix Extra Strength; New hepatitis B prophylactic vaccine, GlaxoSmithKline; HBV prophylactic vaccine (new), GlaxoSmithKline; Hepatitis B prophylactic vaccine (extra strength), GlaxoSmithKline; MPL hepatitis B vaccine, GSK/Corixa; SBAS4-adjuvanted hepatitis B vaccine, GlaxoSmithKline; SBAS4-adjuvanted hepatitis B vaccine, SmithKline Beecham; SBAS4/MPL (HBV vaccine), GlaxoSmithKline/Ribi; SBAS4/MPL (HBV vaccine), SmithKline Beecham/Ribi
Indication
Disease Entry ICD 11 Status REF
Hepatitis B virus infection 1E51.0 Approved [1]
Cross-matching ID
TTD Drug ID
DM0LRU9

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Cell mediated immunity response (CMIR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quattvaxem DMGAZHU Bordetella pertussis infection 1C12.0 Approved [3]
H1N1 pandemic influenza A vaccine DMFUAXT Influenza virus infection 1E30-1E32 Approved [4]
H5N1 influenza vaccine DMMHYLB Human immunodeficiency virus infection 1C62 Approved [5]
Live attenuated influenza vaccine DMX9PIA Influenza virus infection 1E30-1E32 Approved [6]
HEV-239 DMGUC9T Hepatitis E virus infection 1E50.4 Approved [7]
Polyoxidonium DMJAOT1 Infectious disease 1A00-CA43.1 Approved [8]
GSK2592984A DM8QB0T Influenza virus infection 1E30-1E32 Approved [9]
Focetria A(H1N1) DM2PSBE Influenza virus infection 1E30-1E32 Approved [10]
Arepanrix DMVMY7K Influenza virus infection 1E30-1E32 Approved [11]
Celtura DMTIUFA Influenza virus infection 1E30-1E32 Approved [12]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cell mediated immunity response (CMIR) TT3J5ZI NOUNIPROTAC Not Available [2]

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Revaccination with Fendrix or HBVaxPro results in better response rates than does revaccination with three doses of Engerix-B in previous non-responders. Vaccine. 2012 Nov 6;30(48):6734-7.
3 Double-blind study comparing the immunogenicity of a licensed DTwPHib-CRM197 conjugate vaccine (Quattvaxem) with three investigational, liquid formulations using lower doses of Hib-CRM197 conjugate. Vaccine. 2005 Feb 25;23(14):1715-9.
4 How Influenza (Flu) Vaccines Are Made. FLU.gov. 2014.
5 Comparative clinical trial of vaccines against avian influenza. Zh Mikrobiol Epidemiol Immunobiol. 2007 May-Jun;(3):10-6.
6 Flu myths: dispelling the myths associated with live attenuated influenza vaccine. Mayo Clin Proc. 2008 Jan;83(1):77-84.
7 The development of a recombinant hepatitis E vaccine HEV 239. Hum Vaccin Immunother. 2015;11(4):908-14.
8 Effect of polyoxidonium on the phagocytic activity of human peripheral blood leukocytes. Russ J Immunol. 2003 Apr;8(1):53-60.
9 Anti-influenza agents from Traditional Chinese Medicine. Nat Prod Rep. 2010 Jan;27(12):1758-80.
10 Influenza A/H1N1 MF59 adjuvanted vaccine in pregnant women and adverse perinatal outcomes: multicentre study. BMJ. 2013 Feb 4;346:f393.
11 Comparison of Pandemrix and Arepanrix, two pH1N1 AS03-adjuvanted vaccines differentially associated with narcolepsy development. Brain Behav Immun. 2015 Jul;47:44-57.
12 A prospective observational safety study on MF59( ) adjuvanted cell culture-derived vaccine, Celtura( ) during the A/H1N1 (2009) influenza pandemic. Vaccine. 2012 Oct 5;30(45):6436-43.